Journal article
Addition of transcranial direct current stimulation to quadriceps strengthening exercise in knee osteoarthritis: A pilot randomised controlled trial
WJ Chang, KL Bennell, PW Hodges, RS Hinman, CL Young, V Buscemi, MB Liston, SM Schabrun
Plos One | PUBLIC LIBRARY SCIENCE | Published : 2017
Abstract
A randomised, assessor- and participant-blind, sham-controlled trial was conducted to assess the safety and feasibility of adding transcranial direct current stimulation (tDCS) to quadriceps strengthening exercise in knee osteoarthritis (OA), and provide data to inform a fully powered trial. Participants were randomised to receive active tDCS+exercise (AT+EX) or sham tDCS+exercise (ST+EX) twice weekly for 8 weeks whilst completing home exercises twice per week. Feasibility, safety, patient-perceived response, pain, function, pressure pain thresholds (PPTs) and conditioned pain modulation (CPM) were assessed before and after treatment. Fifty-seven people were screened for eligibility. Thirty ..
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Awarded by National Health and Medical Research Council of Australia
Awarded by Australian Research Council
Funding Acknowledgements
This trial was funded by Arthritis Australia (The Zimmer Australia Grant).W-JC(1094434), PWH (1002190), KLB (1058440), MBL (1059116) and SMS (1105040) receive salary support from the National Health and Medical Research Council of Australia, RSH from the Australian Research Council (FT#130100175) and VB from a Western Sydney University Postgraduate Research Award. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.